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Autoimmune Screening Test (ANA with Reflex)

About the Test

This test detects antinuclear antibodies (ANAs) in your blood, which may indicate the presence of an autoimmune disease. If ANAs are found, additional tests will be performed using the same sample to help identify the specific type of autoimmune condition and guide next steps with your healthcare provider.

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Understanding the Process

Allow us to guide you through the blood testing process, ensuring clarity and understanding:

Step 1

Sample
Collection

Step 2

Laboratory
Analysis

Step 3

Data
Interpretation

Step 4

Report
Delivery

How to Get Started

Take charge of your health by leveraging the insights offered by comprehensive blood testing at Amerilab. Contact your health-care provider to discuss the diverse range of blood testing services available.

What to Expect During Testing

Preparation

No special preparation is required.

Blood Sample

This test includes the following process:

  • An ANA Screen Immunofluorescence Assay (IFA) is done first to look for antinuclear autoantibodies in human cells.
  • If the ANA Screen IFA is positive, testing will occur to look for dsDNA, Sm/RNP, RNP, Sm, and Chromatin antibodies. If any of those five antibodies are positive, the cascade stops, and the results are reported.
  • If all five of those antibodies are negative, testing will continue and look for SSA, SSB, Scl-70, and Jo-1 antibodies. If any of those four antibodies are positive, the cascade stops, and the results are reported.
  • If all four of those antibodies are negative, testing will continue and look for Ribosomal P and Centromere B.

Please note, after the initial ANA Screen by IFA, testing will stop when the first positive antibody result(s) in a group are found. It is possible that antibodies in subsequent groups are also positive, but will not be tested, or reported.

After you provide your specimen, it generally takes up to 5 business days to process and release your test results. However, processing times may vary. Your test results will be available in a clear and easy-to-read report. If your results differ from expected ranges, you may receive an alert call from an independent healthcare coordinator. Independent physicians are available to discuss questions or concerns you may have regarding your results.